SQ-LNS provision resulted in a 12% reduction in stunting, 14% reduction in wasting, 18% reduction in low mid-upper arm circumference, 14% reduction in acute malnutrition, 13% reduction in underweight, and 9% reduction in small head size.
SQ-LNS decreased the prevalence of anemia by 16%, iron deficiency by 56%, and iron deficiency anemia by 64%. It also led to a 7% increase in plasma retinol binding protein and a 56% reduction in vitamin A deficiency.
SQ-LNS significantly improved language, social-emotional, and motor development scores, reduced the prevalence of children in the lowest decile of these scores, and increased the prevalence of children walking without support at 12 months.
Children receiving SQ-LNS showed a 12-14% lower prevalence of stunting, wasting, and underweight, a 16% lower prevalence of anemia, and a 64% lower prevalence of iron-deficiency anemia. Additionally, they were 16-19% less likely to score in the lowest decile for language, social-emotional, and motor development compared to control groups.
SQ-LNS led to a 31% reduction in severe wasting and a 17% reduction in severe stunting among children.
Up to 23% reduction in measles-attributable mortality among wasted children, and a 64-66% reduction in measles infections and mortality when combining wasting treatment with mass supplementation and increased vaccination coverage.
Higher intakes of fiber, folate, vitamin C, and iron, along with a potentially beneficial cardiovascular risk profile.
HIV negative patients had better treatment outcomes than HIV positive patients, with the highest number of cases admitted in the 6-59 months age group.
Expected positive outcomes include improved executive functions (EFs) and emotion regulation (ER) in malnourished children, leading to better cognitive and behavioral development.
Interventions that influenced placental phenotype were associated with improved maternal outcomes (69%) and better offspring birth outcomes (54%).
The study indicates that VAS has been shown to substantially reduce morbidity and mortality in preschool-age children, particularly in regions with high prevalence of VAD. Tracking VAS coverage can help identify communities with low coverage, leading to targeted interventions that improve child health outcomes.
Diets with a higher %PP are associated with lower environmental impacts and improved health outcomes, including reduced risks of cardiovascular diseases and cancers. Nutrient-adequate diets can be achieved with a %PP of up to 70% without significant dietary departure.
The fortified nutrient bar significantly increased B12 concentrations in children (median +91 pmol/l) and the yogurt increased B12 in adults (median +38 pmol/l) compared to placebo. Homocysteine levels also fell significantly with B supplementation.
MQ-LNS increased weight-for-length z-scores (WLZ) by +0.09 and reduced the prevalence of wasting (WLZ < -2) with a ratio of 0.89, but had no significant effect on height-for-age z-scores (LAZ) or stunting.
By 12 months corrected age, 5% of very preterm and 10% of moderately preterm infants were overweight. The study found that feeding type at 4 months corrected age predicted body mass index z-scores at 12 months corrected age for very preterm infants, indicating a relationship between feeding practices and growth outcomes.
The intervention led to significant improvements in height gain velocities (2.1-fold in water group, 2.5-fold in toned milk group), better anthropometric and body composition parameters, reduced cases of anaemia and morbidity, and improved cognitive test scores (1.6-fold and 2-fold increases in groups I and II, respectively).
Raising awareness about ORS usage among caregivers could significantly reduce morbidity and mortality associated with malnutrition and diarrhea, improving overall health outcomes for under-5 children.
Expected positive outcomes include improved micronutrient status, increased hemoglobin concentrations, reduced prevalence of micronutrient deficiencies and anemia, and enhanced child growth and development.
The intervention modestly increased length-for-age z-score (LAZ) by 0.16 standard deviations and reduced stunting by 20% at age 18 months.
Improved accuracy in maternal weight perception may lead to healthier feeding practices, potentially reducing the risk of childhood obesity and associated health issues.
The study found no significant change in alpha or beta diversity of the gut microbiome after treatment, indicating that gastric acid suppression did not adversely affect overall microbial diversity in the short term.
Implementing family-centered care has been shown to improve the quality of life for children with diabetes, enhance parental involvement in disease management, reduce hospital stay lengths, and strengthen parent-child bonding.
Positive outcomes include improved treatment satisfaction among parents (47% satisfied), and the therapy is considered safe for pediatric patients with special needs, with infrequent and mild side effects.
Increased dietary diversity scores among adults and children, reduced anemia rates in children under 2 years, and improved child development scores in intervention villages compared to control villages.
The study found that maternal depression was significantly associated with a higher odds of moderate/severe chronic undernutrition in children (OR = 2.67; 95% CI 1.16-6.16).
The study found that integrating pediatrician and parental perspectives improved the identification of children at risk for developmental disorders, with 15.8% of infants presenting warning signs and a notable correlation between parental distress and child development issues.
Improved father's involvement in child feeding, decreased severe cases of undernutrition, and enhanced community-level nutrition service integration.
Significant reductions in enteric pathogen prevalence were observed, particularly among children born after the intervention, with a notable decrease in Shigella and Trichuris prevalence.
The study suggests that addressing hereditary and social environmental factors can enhance early detection and treatment of SM, potentially improving outcomes for affected children.